Exposure to noise from road traffic can increase the risk of stroke, particularly in those aged 65 years and over, according to a study published online on Wednesday 26 January in the European Heart Journal [1]. The study, which is the first to investigate the links between road traffic noise and the risk of stroke, […]
Eating more fruit and vegetables is linked to a lower risk of dying from ischaemic heart disease
A European study investigating the links between diet and disease has found that people who consume more fruit and vegetables have a lower risk of dying from ischaemic heart disease – the most common form of heart disease and one of the leading causes of death in Europe. However, the authors point out that a […]
Important message for journalists about reorganisation of our media databases
We are re-organising our media databases for 2011 to ensure that: a) they only include journalists who want to be on them, b) that you are receiving information on the areas you are interested in, and c) everyone who is on our databases has agreed to abide by our embargoes. We have emailed all our […]
Stand up, move more, more often: study finds more breaks from sitting are good for waistlines and hearts
It is becoming well accepted that, as well as too little exercise, too much sitting is bad for people’s health. Now a new study has found that it is not just the length of time people spend sitting down that can make a difference, but also the number of breaks that they take while sitting […]
Lower levels of education are associated with increased risks of heart failure
Results from a large European study suggest that poorly educated people are more likely to be admitted to hospital with chronic heart failure than the better educated, even after differences in lifestyle have been taken into account. The study is published online today (Thursday 9 December) in the European Heart Journal [1]. Researchers followed 18,616 […]
Tricyclic anti-depressants linked to increased risk of heart disease
Research that followed nearly 15,000 people in Scotland has shown that a class of older generation anti-depressant is linked to an increased risk of cardiovascular disease (CVD). The study showed that tricyclic anti-depressants were associated with a 35% increased risk of CVD, but that there was no increased risk with the newer anti-depressants such as […]
Researchers find new target for stopping tumours developing their own blood supply: phase I trial shows first drug to inhibit ALK-1 receptor is safe and effective
Researchers have found that a newly developed drug, which is aimed at a particular receptor involved in the development of blood vessels that sustain tumour growth, is active in patients with advanced cancers and, in some cases, has halted the progress of the disease. The drug, ACE-041, targets a different molecular pathway to other anti-angiogenesis […]
Cough medicine could help doctors identify how breast cancer patients metabolise tamoxifen, enabling them to improve individual treatments
Cough medicine could be used as way of predicting how well individual patients metabolise tamoxifen used in the treatment of their breast cancer, according to new research presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin today (Friday). The findings suggest that it could be possible to use cough […]
New drug targets vitamin D receptors in hormone resistant prostate cancers: promising results from first clinical trial
A new anti-cancer drug aimed at vitamin D receptors on cancer cells has prompted encouraging responses in the levels of PSA (prostate specific antigen) in men with prostate cancer that has become resistant to hormonal therapies. Results of the phase II(a) clinical trial will be presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets […]
PARP inhibitor, MK-4827, shows anti-tumour activity in first trial in humans
A new drug that targets proteins responsible for helping cancer cells to repair damage to their DNA has shown promising anti-tumour activity in its first trial in humans. Some patients with a range of solid tumours, many of whom had been treated unsuccessfully for their cancer with other therapies, have seen their tumours shrink or […]