Google Street View reveals how built environment correlates with risk of cardiovascular disease

Researchers have used Google Street View to study hundreds of elements of the built environment, including buildings, green spaces, pavements and roads, and how these elements relate to each other and influence coronary artery disease in people living in these neighbourhoods. Their findings, published in the European Heart Journal [1], show that these factors can […]

Breast cancer patients can safely avoid extensive removal of lymph nodes if they respond well to primary systemic treatment

Milan, Italy: Patients with breast cancer that has started to spread to the lymph nodes in the armpit can safely avoid extensive removal of the lymph nodes if their treatment is tailored to their response to cancer-killing therapies such as chemotherapy before surgery. In a presentation to the 14th European Breast Cancer Conference in Milan, […]

Low-dose radiotherapy boost helps prevent local recurrence with better cosmetic outcomes in young breast cancer patients

Milan, Italy: The vast majority of young patients given a low-dose boost of radiotherapy to the site where their breast cancer was removed in addition to whole breast radiotherapy, remained free of local recurrence after ten years, according to results of the ‘Young boost trial’ presented at the 14th European Breast Cancer Conference. Patients treated […]

AI tool predicts risk of side effects after surgery and radiotherapy in breast cancer patients

Phase 3 clinical trial starts later this year Milan, Italy: A team of international researchers have developed an artificial intelligence (AI) tool that can predict which breast cancer patients may be at risk of side effects after surgery and radiotherapy. Dr Tim Rattay told the 14th European Breast Cancer Conference (EBCC14) in Milan that the […]

A combined PET-MRI scan could improve treatment for patients with early breast cancer

Milan, Italy: Using a combined scanning technique on patients with early-stage breast cancer improved treatment in almost three out of ten cases in a trial presented at the 14th European Breast Cancer Conference. Using the combined positron emission tomography-magnetic resonance imaging (PET-MRI) scans enabled doctors to spot signs that a patient’s tumour had begun to […]

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

Milan, Italy: New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status. The findings, presented at the 14th European Breast Cancer Conference (EBCC 14), add to information […]

Addition of atezolizumab to chemotherapy after surgery does not improve survival for triple negative breast cancer

Final analysis of the ALEXANDRA/IMpassion030 phase 3 trial Milan, Italy: Patients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their post-surgery chemotherapy treatment, according to the results of a large phase 3 clinical trial presented at the 14th European Breast Cancer Conference. Triple negative breast cancer, so-called because the cancer […]

Exercise helps patients with advanced breast cancer, especially if they are suffering with pain

Milan, Italy: Taking part in an exercise programme reduced pain and fatigue, and improved quality of life for people with metastatic breast cancer, according to new results of a trial presented at the 14th European Breast Cancer Conference. Although patients of all ages benefitted from exercise, researchers saw the greatest improvement among patients aged under […]

Genetic test identifies patients with triple negative breast cancer who are unlikely to respond to immunotherapies

New results from the I-SPY2 phase 2 clinical trial Milan, Italy: Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs. This means that patients who are unlikely to respond to these drugs can avoid the adverse side effects associated with them and […]

Families of men with fertility problems show distinct patterns of increased risk for several types of cancer

For the first time researchers have identified patterns of risk for several different types of cancer in men with fertility problems and their families. The study, which is published in Human Reproduction [1], one of the world’s leading reproductive medicine journals, found that families of men who have very few or no sperm in their […]