Cough medicine could be used as way of predicting how well individual patients metabolise tamoxifen used in the treatment of their breast cancer, according to new research presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin today (Friday). The findings suggest that it could be possible to use cough […]
Category: Cancer
New drug targets vitamin D receptors in hormone resistant prostate cancers: promising results from first clinical trial
A new anti-cancer drug aimed at vitamin D receptors on cancer cells has prompted encouraging responses in the levels of PSA (prostate specific antigen) in men with prostate cancer that has become resistant to hormonal therapies. Results of the phase II(a) clinical trial will be presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets […]
PARP inhibitor, MK-4827, shows anti-tumour activity in first trial in humans
A new drug that targets proteins responsible for helping cancer cells to repair damage to their DNA has shown promising anti-tumour activity in its first trial in humans. Some patients with a range of solid tumours, many of whom had been treated unsuccessfully for their cancer with other therapies, have seen their tumours shrink or […]
Tiny Trojan horses attack brain cancer cells
Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier – a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell. The blood-brain barrier is formed by a network of […]
Researchers map the way to personalised treatment for ovarian cancer
Researchers have shown that point mutations – mis-spellings in a single letter of genetic code – that drive the onset and growth of cancer cells can be detected successfully in advanced ovarian cancer using a technique called OncoMap. The finding opens the way for personalised medicine in which every patient could have their tumour screened, […]
Personalised medicine: tumour analysis reveals new opportunities for existing cancer drugs
Targeted cancer therapies such as trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva) could be used to treat a wider range of cancers than previously thought, according to new research presented today (Wednesday) at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin. Scientists in the USA have studied 20 genes that […]
Scientists identify potential new target for treating triple negative breast cancer
Scientists believe they may have found a new target for treating triple negative breast cancer – one of the more difficult breast cancers to treat successfully and for which there is no targeted therapy at present. Triple negative breast cancer (TNBC) is a cancer that does not express receptors for oestrogen (ER), progesterone (PR) or […]
MEPs and health professionals call for urgent action to tackle chronic diseases
Members of the European Parliament are calling on the Presidency of the EU and Member States to tackle urgently the problem of chronic non-communicable diseases that are responsible for 86% of all deaths in the WHO European Region. Their call is supported by an alliance of European health professionals, including ECCO – the European CanCer […]
Intrauterine devices (IUDs) can be used to treat endometrial cancer
Intrauterine devices, originally developed as contraceptives, can also be used to treat and cure cancer of the endometrium according to new research published online in the cancer journal, Annals of Oncology [1] today (Wednesday 29 September). The finding opens the way for young women with the disease, which affects the lining of the womb, to […]
Cancer deaths fall, but prevention still lags behind; short-term economic outlook must not damage long-term health, researchers say
Although overall mortality from cancer is decreasing in the European Union, its incidence increased by almost 20%, from 2.1 million new cases in 2002 to 2.5 million in 2008, says a special issue [1] of the European Journal of Cancer (the official journal of ECCO – the European CanCer Organisation) on cancer prevention, published today […]